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HCA-Vision for Fast High Content Analysis

HCA-Vision is an automated image analysis software package that rapidly and reproducibly measures functional features of neuronal cells in 2D images.

Who it’s for

  • Neuroscience researchers in universities, research institutes, hospitals etc
  • Researchers in life science and pharmaceutical companies conducting target identification/validation and compound screening

What it does

HCA-Vision guides the user in the process of choosing optimal parameters for the automated segmentation of neuron bodies and neurites. It delivers quantitative measures and statistics that are biologically relevant.

For example, the neurite outgrowth module of HCA-Vision measures important morphological properties of neuronal cells, such as:

  • number of branching points
  • total neurite length
  • number of branch layers
  • number of primary branches

View a Flash presentation about this software.  
NOTE: It requires that you have the Flash Player. It is set to 1280 x 1024 resolution and is 4MB in size. Set your browser to full screen mode (F11).

Features

  • available as a complete stand-alone package or as modules for integration into third-party systems
  • images and numerical results can be exported in a wide range of formats
  • full batch processing capabilities
  • provides detailed, relevant information about cells
  • optimised for speed
  • easy to use – parameters are intuitive, can tune parameters and immediately see effects, step-by-step/Wizard-based process, interactive with real-time response
  • can store parameter profiles for similar assay conditions
  • statistics are available per cell or at population level
  • based on .NET technology

New modules will be developed. For example, modules are planned in the area of cell co-culture analysis and nuclear damage. Talk to us about these.

For HCA-Vision users, CSIRO provides:

HCA-Vision on rat brain neuron

Above: Primary rat brain neuron showing a high degree of complexity of neurite branching as measured by HCA-Vision (courtesy of Prof P Doherty, Kings College London)

  • extensive on-line help
  • tutorials on the web
  • email technical support

HCA-Vision is competitively priced. We also offer, for a fee, customisation of the product.

Try it for free

You can try HCA-Vision for free. To download a demo version of HCA-Vision or for more information, please click here.

Contact

Dr Pascal Vallotton
Leader, Biotech Imaging
+61 2 9325 3208
pascal.vallotton@csiro.au

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Last updated July 02, 2008 10:27 AM
Ryan.Lagerstrom@csiro.au

 

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