 Application
Areas
Biotechnology
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Microarray Spot Detection: DNA
microarrays, often called DNA Chips, are used to analyse the
expression level of particular genes. We have developed an advanced
microarray spot detection and characterisation package, called Spot,
which extracts more meaningful numerical formation than that from
existing packages.
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Cellular
Screening: We have developed image analysis algorithms for High
Content Analysis (HCA) of multiband fluorescence microscope images of
cells for target identification and validation and compound
screening in drug discovery. Our software can rapidly produce
reliable measurements on cellular characteristics such as shape,
neurite outgrowth, changes in adhesion and other morphological
changes.
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Protein Gel
Analysis: Proteomics, an area of increasing interest to the
biotechnology community, is the study of the structure and function of
proteins. Two dimensional (2D) electrophoresis gel images can be used
to identify and characterise many forms of a particular protein
encoded by a single gene. We have the skills in segmentation and
registration necessary to analyse these highly complex gel
images. We are collaborating with Proteome Systems Ltd (PSL) to
facilitate the interface between PSL's protein array technology and
automated technologies for protein analysis.
Health
Asset Monitoring
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Roadcrack:
We have developed an automatic road crack detection vehicle for the
Roads and Traffic Authority in NSW, with the aim of gaining a vast
improvement in the quantity and the quality of information on cracking
in roads and highways.
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Corridor
Mapping: We have carried out several studies for Powercor
Australia Ltd to develop a cost effective airborne image capture and
processing system to automatically measure the clearance of trees from
powerlines. Power companies in Australia (and many other countries)
are required to maintain a regulated clearance space around all
powerlines for bushfire mitigation and safety purposes.
Exploration and Mining
Other Areas
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Fibre Sizing:
We have developed software to measure the diameter and length of fibre
glass fibres for the insulation industry.
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Symmetry
Detection: We have skills in the detection of symmetry in images.
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Hardwood Quality:
We have automated procedures to measure wood fibre properties.
For further information, please contact:
Pascal Vallotton
Leader, Biotech Imaging
CSIRO Mathematics, Informatics and Statistics
Locked Bag 17, North Ryde NSW 1670 AUSTRALIA
Phone: +61 (0)2 9325 3208
Fax: +61 (0)2 9325 3200
Email: pascal.vallotton@csiro.au
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