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Health and Biotechnology

From understanding gene expression to optimising patient flows in hospitals, CSIRO's mathematicians and statisticians are helping the health and biotechnology industries to exploit the knowledge hidden in their data. Here are some examples:

Bioinformatics

The biotechnology industry relies on exploiting the often complex and very large data sets generated by microarray and other technologies. Using microarray technology it is now possible to measure gene expression levels for over 30,000 genes in a single experiment.

We are developing and applying world leading new techniques for extracting meaningful information from gene expression data. This type of analysis will lead to new insights into the mechanisms of disease, leading to new diagnostic technologies and new drugs for treatment or disease.

Read more:

Image Analysis for drug discovery and diagnostics

In biotechnology and health there is an enormous amount of information contained in images, in everything from samples on microscope slides to cellular assays used in drug discovery.

CSIRO statisticians have expertise in automated extraction and analysis of quantitative information from digital images. The applications of this range from speeding up the drug discovery process to diagnosing skin cancer.

Read more:

Optimising patient flows in hospitals

animation of patient flows in an emergency departmentCSIRO mathematicians with expertise in operations research are helping to minimise costs and optimise operational performance of healthcare services through whole of system research in the area of health service operational efficiency.

Some of the factors involved in optimising performance of the healthcare system include identifying demand using epidemiological forecasting, determining the allocation of resources to meet this demand and then scheduling the provision of these resources.

Animation of patient flows in an emergency department (best viewed using IE)

The mathematical challenge is to develop assignment and scheduling algorithms that can seamlessly deal with the different degrees of uncertainty in the healthcare system and provide planners and managers with the tools to meet patient needs.

These decision systems will support healthcare management in areas such as:

  • allocation of beds to medical programs
  • scheduling of operating theatres
  • assignment of patients to beds in wards
  • flow of patients between facilities

Read more:

Further information on our research in health and biotechnology

Contact

Mr Andrew Dingjan
Business Development Manager
CSIRO Mathematics, Informatics and Statistics Private Bag 33
Clayton South, VIC 3169
+61 3 9545 8040
Andrew.Dingjan@csiro.au

Last Updated Tuesday, January 18, 2011 12:22 PM CMIS-Communicators@csiro.au

 

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